Abstract

Research on freshly-excised malignant breast tissues and surrounding normal tissues in an in vitro impedance cell has shown that breast tumors have significant differences in the frequency spectrum of the admittivity between normal or nonmalignant tissues and tumors [4]. This contrast may provide a basis for breast cancer detection using frequency scanning in electrical impedance imaging. We present a method for analyzing electrical impedance spectroscopy (EIS) data from breast cancer patients with co-registered EIT image and Tomosynthesis image. We can find a region of interest by Tomosynthesis and analyze the admittivity spectra of the corresponding region by 3-D EIT reconstructions. An EIS plot is generated and displayed for each of the reconstructed voxels or mesh elements at 5 frequencies: 5, 10, 30, 100 and 300 kHz. The distribution of the admittivity spectra for normal breast tissue from patients are compared with those from patients with breast tumor as verified by the pathology report of a biopsy samle. The potential usefulness of this analysis is to distinguish breast cancer from normal tissue with the admittivity data. It is also possible that suspicious regions may be found by the EIS plots and then further analyzed by Tomosynthesis.

Notes

Poster presented at the 2007 Thrust R2A Multi-View Tomographic Methods Conference

Keywords

Tomosynthesis, breast cancer

Subject Categories

Diagnostic imaging, Tomography

Disciplines

Biomedical Engineering and Bioengineering

Publisher

Bernard M. Gordon Center for Subsurface Sensing and Imaging Systems (Gordon-CenSSIS)

Publication Date

2007

Rights Holder

Bernard M. Gordon Center for Subsurface Sensing and Imaging Systems (Gordon-CenSSIS)



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