The Bernard M. Gordon Center for Subsurface Sensing and Imaging Systems is a multi-university NSF ERC founded in 2000. Its mission is to revolutionize the existing technology for detecting and imaging biomedical, environmental, or geophysical objects or conditions that lie underground or underwater, or are embedded in the human body. The Center's unified, multidisciplinary approach combines expertise in wave physics, sensor engineering, image processing, and inverse scattering to create new sensing modalities and prototypes that may be transitioned to industry partners for further development. A key element of the CenSSIS education mission is to immerse students in efforts to solve important real-world problems such as noninvasive breast cancer detection or underground pollution assessment. The Center's academic partners are Northeastern University, Boston University, Rensselaer Polytechnic Institute, and the University of Puerto-Rico, Mayagüez. Strategic affiliates include Massachusetts General Hospital, Lawrence Livermore and Idaho National Laboratories, Woods Hole Oceanographic Institution, and Memorial Sloan-Kettering Cancer Center.